1-(Pyridin-2-ylmethyl)-1H-indazol-5-amine → tert-Butyl 3-cyano-4-{[1-(pyridin-2-ylmethyl)-1H-indazol-5-yl]amino}-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

HRID 308060Notes

Reaction equation

HRID 308060 reaction equation
[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]#[N:9])[s:10][c:11]1[c:16]2[CH2:15][CH2:14][N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12]1.[n:24]1[c:25]([CH2:30][n:31]2[n:32][cH:33][c:34]3[cH:35][c:36]([NH2:40])[cH:37][cH:38][c:39]23)[cH:26][cH:27][cH:28][cH:29]1>>[c:2]1([NH:40][c:36]2[cH:35][c:34]3[cH:33][n:32][n:31]([CH2:30][c:25]4[n:24][cH:29][cH:28][cH:27][cH:26]4)[c:39]3[cH:38][cH:37]2)[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8]#[N:9])[s:10][c:11]1[c:16]2[CH2:15][CH2:14][N:13]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12]1

Participants

3

Reactant 2

HCID 219523661-(Pyridin-2-ylmethyl)-1H-indazol-5-amineHCID 58116935tert-Butyl 4-chloro-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

Product 1

HCID 58116789tert-Butyl 3-cyano-4-{[1-(pyridin-2-ylmethyl)-1H-indazol-5-yl]amino}-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

Sources & evidence

ORD record
ord-36d9110596f843c0bf9481cec2305706
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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