Acetone → Acetic acid 6,7-dimethyl-2-(2-morpholin-4-yl-acetyl)-benzofuran-5-yl ester

HRID 308197Notes

Reaction equation

HRID 308197 reaction equation
[Br:1][CH2:2][C:3](=[O:4])[c:5]1[o:6][c:7]2[c:8]([cH:9]1)[cH:10][c:11]([O:16][C:17]([CH3:18])=[O:19])[c:12]([CH3:15])[c:13]2[CH3:14].[C:26](=[O:27])([O-:28])[O-:29].[CH2:20]1[CH2:21][O:22][CH2:23][CH2:24][NH:25]1.[CH3:32][C:33](=[O:34])[CH3:35].[K+:30].[K+:31]>>[CH2:2]([C:3](=[O:4])[c:5]1[o:6][c:7]2[c:8]([cH:9]1)[cH:10][c:11]([O:16][C:17]([CH3:18])=[O:19])[c:12]([CH3:15])[c:13]2[CH3:14])[N:25]1[CH2:20][CH2:21][O:22][CH2:23][CH2:24]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 8083MorpholineHCID 19660Carbonate IonHCID 101719982-Bromo-1-(5-acetoxy-6,7-dimethyl-benzofuran-2-yl)-ethanone

Product 1

HCID 10236780Acetic acid 6,7-dimethyl-2-(2-morpholin-4-yl-acetyl)-benzofuran-5-yl ester

Sources & evidence

ORD record
ord-7e196cb604254b61bddd83c1b7a2c0b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…