4-tert-Butyl-1-fluoro-2-nitrobenzene → 5-Tert-butyl-2-fluoroaniline

Participants

Reaction Steps

To 4-tert-butyl-1-fluoro-2-nitrobenzene in methanol was added a catalytic amount of palladium on carbon (10%). The mixture was allowed to stir for 1 h at room temperature under an atmosphere of hydrogen. Mixture was filtered though celite and concentrated to afford 5-tert-butyl-2-fluorobenzenamine.

Provenance & Evidence