6-Chloro-3-pyridinecarbonitrile → 6-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)amino]-pyridine-3-carbonitrile

HRID 308244Notes

Reaction equation

HRID 308244 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[cH:6][cH:7][c:8]1-[c:9]1[c:10](-[c:11]2[nH:12][cH:13][cH:14][n:15]2)[cH:16][n:17][c:18]([CH2:19][CH2:20][NH2:21])[n:22]1.[Cl:23][c:24]1[n:25][cH:26][c:27]([C:30]#[N:31])[cH:28][cH:29]1.[Cl:32][c:33]1[c:34](-[c:40]2[n:41][c:42]([NH:51][CH2:52][CH2:53][NH:54][c:55]3[cH:56][cH:57][c:58]([N+:59]([O-:60])=[O:61])[c:62]([O:63][CH3:64])[n:65]3)[n:43][cH:44][c:45]2-[c:46]2[nH:47][cH:48][cH:49][n:50]2)[cH:35][cH:36][c:37]([Cl:39])[cH:38]1>>[c:24]1([NH:54][CH2:53][CH2:52][NH:51][c:42]2[n:41][c:40](-[c:34]3[c:33]([Cl:32])[cH:38][c:37]([Cl:39])[cH:36][cH:35]3)[c:45](-[c:46]3[n:47][cH:48][cH:49][nH:50]3)[cH:44][n:43]2)[n:25][cH:26][c:27]([C:30]#[N:31])[cH:28][cH:29]1

Participants

4

Reactant 3

HCID 51520946-Chloro-3-pyridinecarbonitrileHCID 22142635[4-(2,4-Dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(6-methoxy-5-nitro(2-pyridyl)) amino]ethyl}amineHCID 542317734-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-ylethylamine

Product 1

HCID 221424686-[(2-{[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]amino}ethyl)amino]-pyridine-3-carbonitrile

Sources & evidence

ORD record
ord-692f8a1f9ff846278d25540fe947145b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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