Methanol → 4-[(1-cyclohexyl-3,4-dihydroisoquinolin-2(1H)-yl)carbonyl]piperidin-4-ol
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([C:15](=[O:16])[N:17]2[CH:18]([CH:27]3[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]3)[c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]3[CH2:25][CH2:26]2)[CH2:12][CH2:13]1.[CH3:33][OH:34].[Pd:35]>>[NH:8]1[CH2:9][CH2:10][C:11]([OH:14])([C:15](=[O:16])[N:17]2[CH:18]([CH:27]3[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]3)[c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]3[CH2:25][CH2:26]2)[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-2b491738d4d0415ba4afab7dfc546153
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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