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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 308306Generated: October 29, 2026

Dichloromethane → 1'-(2,2,2-trifluoroacetyl)spiro[indene-1,4'-piperidin]-3(2H)-one

https://huagongshe.com/reaction/308306

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylamineHCID 8471—
Reactant4-(Dimethylamino)pyridineHCID 14284—
ReactantTert-butyl 3-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylateHCID 18673579—
Product1'-(2,2,2-trifluoroacetyl)spiro[indene-1,4'-piperidin]-3(2H)-oneHCID 19366992—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-f40edcde839e4ba0ac1ee555ef9e8699
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)