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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 308430Generated: October 25, 2026

Methylamine → 1,1,1-Trifluoro-2-[4-[2-(methylaminomethyl)-4-thiophen-2-ylsulfonylpiperazin-1-yl]phenyl]propan-2-ol

https://huagongshe.com/reaction/308430

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantTetrahydrofuranHCID 8028—
Reactant(4-(2-Thiophenylsulfonyl)-1-(4-(2,2,2-trifluoro-1-hydroxy-1-methylethyl)phenyl)-2-piperazinyl)methyl methanesulfonateHCID 86670324—
Product1,1,1-Trifluoro-2-[4-[2-(methylaminomethyl)-4-thiophen-2-ylsulfonylpiperazin-1-yl]phenyl]propan-2-olHCID 77148488—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-4d744a72f76842309dac1211ec7f048d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)