Sodium ion → 4-(4-{5-Methyl-4-[2-(2-methyl-piperidin-1-yl)-ethyl]-oxazol-2-yl}-phenyl)-pyridine

HRID 308560Notes

Reaction equation

HRID 308560 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]([CH3:22])[c:11]([CH2:13][CH2:14][N:15]3[CH:16]([CH3:21])[CH2:17][CH2:18][CH2:19][CH2:20]3)[n:12]2)[cH:6][cH:7]1.[C:32](=[O:33])([O-:34])[O-:35].[CH2:38]1[O:39][CH2:40][CH2:41][O:42][CH2:43]1.[Na+:36].[Na+:37].[n:23]1[cH:24][cH:25][c:26]([B:29]([OH:30])[OH:31])[cH:27][cH:28]1>>[c:2]1(-[c:26]2[cH:25][cH:24][n:23][cH:28][cH:27]2)[cH:3][cH:4][c:5](-[c:8]2[o:9][c:10]([CH3:22])[c:11]([CH2:13][CH2:14][N:15]3[CH:16]([CH3:21])[CH2:17][CH2:18][CH2:19][CH2:20]3)[n:12]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 2734379(Pyridin-4-yl)boronic acidHCID 115160701-{2-[2-(4-Bromo-phenyl)-5-methyl-oxazol-4-yl]-ethyl}-2-methylpiperidine

Product 1

HCID 589514794-(4-{5-Methyl-4-[2-(2-methyl-piperidin-1-yl)-ethyl]-oxazol-2-yl}-phenyl)-pyridine

Sources & evidence

ORD record
ord-b1cd7593b7ca4d0fae23775db2dab6c3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…