2-Methyl-4-methoxyaniline → N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(4-methoxy-2-methylphenyl)-2,4-pyrimidinediamine

HRID 308561Notes

Reaction equation

HRID 308561 reaction equation
[CH3:20][O:21][c:22]1[cH:23][c:24]([CH3:29])[c:25]([NH2:26])[cH:27][cH:28]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1>>[c:2]1([NH:26][c:25]2[c:24]([CH3:29])[cH:23][c:22]([O:21][CH3:20])[cH:28][cH:27]2)[n:3][cH:4][c:5]([F:19])[c:6]([NH:8][c:9]2[cH:10][c:11]3[c:12]([cH:13][cH:14]2)[O:15][CH2:16][CH2:17][O:18]3)[n:7]1

Participants

3

Reactant 2

HCID 76102-Methyl-4-methoxyanilineHCID 220603622-chloro-5-fluoro-N-(3,4-ethylenedioxyphenyl)-4-pyrimidineamine

Product 1

HCID 22061058N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(4-methoxy-2-methylphenyl)-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-ac7e2fb8045a482899e9ef8529ddc05c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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