Dichloromethane → 1-[2-(2-Dimethylamino-ethyl)-benzo[b]thiophen-3-yl]-1-(5-fluoro-pyridin-2-yl)-ethanol
Reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([F:8])[cH:6][cH:7]1.[CH2:31]([Cl:32])[Cl:33].[CH2:9]([Li:10])[CH2:11][CH2:12][CH3:13].[CH3:14][N:15]([CH2:16][CH2:17][c:18]1[c:19]([C:27]([CH3:28])=[O:29])[c:20]2[c:21]([s:22]1)[cH:23][cH:24][cH:25][cH:26]2)[CH3:30].[CH3:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39]>>[c:2]1([C:27]([c:19]2[c:18]([CH2:17][CH2:16][N:15]([CH3:14])[CH3:30])[s:22][c:21]3[c:20]2[cH:26][cH:25][cH:24][cH:23]3)([CH3:28])[OH:29])[n:3][cH:4][c:5]([F:8])[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-86ec4a87a37a4bdea23bff3dbb4da94f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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