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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 308726Generated: October 26, 2026

Hydrochloric Acid → Methyl 4-bromo-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]-5-[3-[[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]amino]phenyl]thiophene-2-carboxylate

https://huagongshe.com/reaction/308726

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
ReactantTriethylamineHCID 8471—
Reactant2-Chloro-4-(trifluoromethyl)pyrimidineHCID 2773912—
ReactantMethyl 4-bromo-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]-5-[3-(piperidin-4-ylamino)phenyl]thiophene-2-carboxylateHCID 17758124—
ProductMethyl 4-bromo-3-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]-5-[3-[[1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl]amino]phenyl]thiophene-2-carboxylateHCID 68838358—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-d65f5a0a016b4b898fd748617c36e0e3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)