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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 308802Generated: October 29, 2026

Dichloromethane → Methyl 5-(4-(2-((tert-butoxycarbonylamino)methyl)-5-fluorobenzamido)-N-methylbutylsulfonamido)-8-(tosyloxy)-1,6-naphthyridine-7-carboxylate

https://huagongshe.com/reaction/308802

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantHexafluorophosphateHCID 9886—
ReactantDiisopropylethylamineHCID 81531—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant2-[[(tert-Butoxycarbonyl)amino]methyl]-5-fluorobenzoic acidHCID 11065474—
ReactantMethyl 5-(4-amino-N-methylbutylsulfonamido)-8-(tosyloxy)-1,6-naphthyridine-7-carboxylateHCID 86667516—
ProductMethyl 5-(4-(2-((tert-butoxycarbonylamino)methyl)-5-fluorobenzamido)-N-methylbutylsulfonamido)-8-(tosyloxy)-1,6-naphthyridine-7-carboxylateHCID 86667517—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-5db53d5f124b41668a63c9a91f81e11a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)