ethyl 2-(1-benzyl-1H-1,2,3-triazol-4-yl)-4-methylthiazole-5-carboxylate → 4-methyl-2-(1-(4-(trifluoromethyl)benzyl)-1H-1,2,3-triazol-4-yl)thiazole-5-carboxylic acid
Reaction equation
[CH2:1]([n:2]1[cH:3][c:4](-[c:5]2[s:6][c:7]([C:8]([O:9][CH2:10][CH3:11])=[O:12])[c:13]([CH3:14])[n:15]2)[n:16][n:17]1)[c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[CH3:24][c:25]1[n:26][c:27](-[c:35]2[n:36][n:37][n:38]([CH2:40][c:41]3[cH:42][cH:43][c:44]([C:47]([F:48])([F:49])[F:50])[cH:45][cH:46]3)[cH:39]2)[s:28][c:29]1[C:30](=[O:31])[O:32][CH2:33][CH3:34]>>[CH3:24][c:25]1[n:26][c:27](-[c:35]2[n:36][n:37][n:38]([CH2:40][c:41]3[cH:42][cH:43][c:44]([C:47]([F:48])([F:49])[F:50])[cH:45][cH:46]3)[cH:39]2)[s:28][c:29]1[C:30](=[O:31])[OH:32]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5395d120aed4486db677d5e114001467
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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