4-carboxy-2-isobutyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one → 4-hydroxymethyl-2-isobutyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one
Reaction equation
[C:22](=[O:23])([OH:24])[c:25]1[c:26](=[O:45])[n:27]([CH2:41][CH:42]([CH3:43])[CH3:44])[n:28][c:29](-[c:31]2[cH:32][cH:33][c:34]([C:37]([F:38])([F:39])[F:40])[cH:35][cH:36]2)[cH:30]1.[F:1][c:2]1[cH:3][c:4](-[c:5]2[c:6]([CH3:7])[c:8]([OH:9])[c:10](=[O:11])[n:12]([CH2:13][CH:14]([CH3:15])[CH3:16])[n:17]2)[cH:18][cH:19][c:20]1[CH3:21]>>[CH2:22]([OH:23])[c:25]1[c:26](=[O:45])[n:27]([CH2:41][CH:42]([CH3:43])[CH3:44])[n:28][c:29](-[c:31]2[cH:32][cH:33][c:34]([C:37]([F:38])([F:39])[F:40])[cH:35][cH:36]2)[cH:30]1Participants
3
Sources & evidence
- ORD record
- ord-5b29cdc55b384e8fa9ed7630bc7a4c76
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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