HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-Ethynyl-4-hydroxyamino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-3-methyl-tetrahydro-furan-3,4-diol → 2-(4-Hydroxyamino-5-vinyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-3-methyl-tetrahydro-furan-3,4-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-Ethynyl-4-hydroxyamino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-3-methyl-tetrahydro-furan-3,4-diol | HCID 21040835 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Lindlars catalyst | HCID 131709914 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(4-Hydroxyamino-5-vinyl-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-3-methyl-tetrahydro-furan-3,4-diol | HCID 21040828 | — |
Reaction Steps
The title compound from Example 29 is dissolved in THF and placed under hydrogen (1 atm) in the presence of Lindlar's catalyst until one mole of hydrogen is consumed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425547B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-f9c19a0ec1e048cab0e3cb38330568f2 |
| Source note | uspto-grants-2008_09 |