HRID30996

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21072494

未命名化合物

结构：N[C@@H]1C(=O)N(CCOCc2ccccc2)c2ccccc2-c2ccccc21

HCID58972512

未命名化合物

PRODUCTS

生成物

结构：CC(C(=O)NCC(F)(F)C(F)(F)F)C(=O)N[C@@H]1C(=O)N(CCOCc2ccccc2)c2ccccc2-c2ccccc21

HCID58972538

未命名化合物

PROCEDURE

实验过程

Using (S)-7-amino-5-(2-benzyloxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-one and 2-methyl-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid, the title compound was prepared in the same manner as described for example 1c). White solid (89% yield). MS: m/e=490(M+H+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-392403d92af44c1babb71ea705e8ed72
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07425551B2
来源说明: uspto-grants-2008_09

反应 SMILES

[NH2:1][C@@H:2]1[C:8](=[O:9])[N:7]([CH2:10][CH2:11][O:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:6]2[CH:20]=[CH:21][CH:22]=[CH:23][C:5]=2[C:4]2[CH:24]=[CH:25][CH:26]=[CH:27][C:3]1=2.[CH3:28][CH:29]([C:33]([NH:35][CH2:36][C:37]([F:43])([F:42])[C:38]([F:41])([F:40])[F:39])=[O:34])[C:30](O)=[O:31]>>[CH2:13]([O:12][CH2:11][CH2:10][N:7]1[C:8](=[O:9])[C@@H:2]([NH:1][C:30](=[O:31])[CH:29]([CH3:28])[C:33]([NH:35][CH2:36][C:37]([F:42])([F:43])[C:38]([F:39])([F:40])[F:41])=[O:34])[C:3]2[CH:27]=[CH:26][CH:25]=[CH:24][C:4]=2[C:5]2[CH:23]=[CH:22][CH:21]=[CH:20][C:6]1=2)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1