HRID31011

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID79002

1H,1H-Perfluoropropylamine

C3H4F5N

结构：CCOC(C(=O)O)C(=O)N[C@@H]1C(=O)N(CCOCc2ccccc2)c2ccccc2-c2ccccc21

HCID58972534

未命名化合物

PRODUCTS

生成物

结构：CCOC(C(=O)NCC(F)(F)C(F)(F)F)C(=O)N[C@@H]1C(=O)N(CCOCc2ccccc2)c2ccccc2-c2ccccc21

HCID58972527

未命名化合物

PROCEDURE

实验过程

Using N—[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-ethoxy-malonamic acid and 2,2,3,3,3-pentafluoropropylamine, the title compound was prepared in the same manner as described for example 1c. White solid. (82%). MS: m/e=620(M+H+).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cb22431ba06149feb37a73cd0e961253
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07425551B2
来源说明: uspto-grants-2008_09

反应 SMILES

[CH2:1]([O:8][CH2:9][CH2:10][N:11]1[C:17](=[O:18])[C@@H:16]([NH:19][C:20](=[O:28])[CH:21]([O:25][CH2:26][CH3:27])[C:22]([OH:24])=O)[C:15]2[CH:29]=[CH:30][CH:31]=[CH:32][C:14]=2[C:13]2[CH:33]=[CH:34][CH:35]=[CH:36][C:12]1=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:37][C:38]([F:45])([C:41]([F:44])([F:43])[F:42])[CH2:39][NH2:40]>>[CH2:1]([O:8][CH2:9][CH2:10][N:11]1[C:17](=[O:18])[C@@H:16]([NH:19][C:20](=[O:28])[CH:21]([O:25][CH2:26][CH3:27])[C:22]([NH:40][CH2:39][C:38]([F:45])([F:37])[C:41]([F:44])([F:43])[F:42])=[O:24])[C:15]2[CH:29]=[CH:30][CH:31]=[CH:32][C:14]=2[C:13]2[CH:33]=[CH:34][CH:35]=[CH:36][C:12]1=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1