Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,2,3,3,3-Pentafluoropropylamine → 2-Ethoxy-N-[(S)-5-(2-hydroxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-N'-(2,2,3,3,3-pentafluoro-propyl)-malonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,2,3,3,3-Pentafluoropropylamine | HCID 79002 | — |
| 반응물 | N-[(S)-5-(2-Benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-ethoxy-N'-(2,2,3,3,3-pentafluoro-propyl)-malonamide | HCID 58972527 | — |
| 생성물 | 2-Ethoxy-N-[(S)-5-(2-hydroxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-N'-(2,2,3,3,3-pentafluoro-propyl)-malonamide | HCID 24876784 | — |
반응 단계
Using N—[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-ethoxy-N′-(2,2,3,3,3-pentafluoro-propyl)-malonamide and 2,2,3,3,3-pentafluoropropylamine, the title compound was prepared in the same manner as described for example 3. White solid (83%). MS: m/e=530(M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07425551B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-f194d77d882e4395a0e54ec5a58ba580 |
| 출처 메모 | uspto-grants-2008_09 |