HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,3,3,3-Pentafluoropropylamine → (R)-2-Fluoro-N-[(S)-5-(2-methoxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-methyl-N'-(2,2,3,3,3-pentafluoro-propyl)-malonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,3,3,3-Pentafluoropropylamine | HCID 79002 | — |
| Reactant | HCID 58972507 | HCID 58972507 | — |
| Product | (R)-2-Fluoro-N-[(S)-5-(2-methoxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-methyl-N'-(2,2,3,3,3-pentafluoro-propyl)-malonamide | HCID 24875578 | — |
Reaction Steps
Using (S)-2-fluoro-N—[(S)-5-(2-methoxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-2-methyl-malonamic acid and 2,2,3,3,3-pentafluoropropylamine, the title compound was prepared in the same manner as described for example 1c. White solid (71%). MS: m/e=532(M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425551B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-694d5e9e76274c358010101112ac021e |
| Source note | uspto-grants-2008_09 |