HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3,4,4,4-Pentafluorobutan-1-amine → (3,3,4,4,4-Pentafluoro-butyl)-carbamic acid (S)-1-[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-ylcarbamoyl]-ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3,4,4,4-Pentafluorobutan-1-amine | HCID 15754740 | — |
| Reactant | Carbonic acid (S)-1-[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-ylcarbamoyl]-ethyl ester 4-nitro-phenyl ester | HCID 58972494 | — |
| Product | (3,3,4,4,4-Pentafluoro-butyl)-carbamic acid (S)-1-[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-ylcarbamoyl]-ethyl ester | HCID 58972464 | — |
Reaction Steps
Using carbonic acid (S)-1-[(S)-5-(2-benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-ylcarbamoyl]-ethyl ester 4-nitro-phenyl ester and 3,3,4,4,4-pentafluorobutylamine, the title compound was prepared in the same manner as described for example 5c. White solid (97%). MS: m/e=620(M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425551B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-a82fc4f716f14b0781e24873c7888d9a |
| Source note | uspto-grants-2008_09 |