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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 310389Generated: October 26, 2026

Tetrahydrofuran → 1-(4-fluorobenzyl)-4-(5-(hydroxymethyl)-4-methylthiazol-2-yl)-1H-1,2,4-triazol-5(4H)-one

https://huagongshe.com/reaction/310389

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantAluminum CationHCID 104727—
ReactantHydrideHCID 166653—
Reactantethyl 2-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methylthiazole-5-carboxylateHCID 57919964—
Product1-(4-fluorobenzyl)-4-(5-(hydroxymethyl)-4-methylthiazol-2-yl)-1H-1,2,4-triazol-5(4H)-oneHCID 57919904—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-5b0ad079be9b462284897679ab516aca
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)