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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 310432Generated: October 30, 2026

Acetic Acid → 3-[2-[(4-Bromophenyl)-(4-fluorophenylamino)methyl]-5-(tert-butyl-dimethylsilanyloxy)-5-(4-fluorophenyl)pentanoyl]-4-phenyloxazolidin-2-one

https://huagongshe.com/reaction/310432

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantChlorideHCID 312—
Reactant2,3-Dihydroxybutanedioic AcidHCID 875—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantChlorotrimethylsilaneHCID 6397—
ReactantDiisopropylethylamineHCID 81531—
ReactantBisulfiteHCID 104748—
ReactantTitanium cation (4+)HCID 114942—
ReactantN-[(4-Bromophenyl)methylene]-4-fluorobenzenamineHCID 904271—
Reactant3-[5-(tert-Butyldimethylsilanyloxy)-5-(4-fluorophenyl)pentanoyl]4-phenyloxazolidin-2-oneHCID 12111618—
Product3-[2-[(4-Bromophenyl)-(4-fluorophenylamino)methyl]-5-(tert-butyl-dimethylsilanyloxy)-5-(4-fluorophenyl)pentanoyl]-4-phenyloxazolidin-2-oneHCID 22252067—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-e260796746c24d1f9427ea3adff2f93b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)