HCID 21072482, compound → HCID 58972522, compound

HRID 31050Notes

Reaction equation

HRID 31050 reaction equation
[NH2:1][C@@H:2]1[C:8](=[O:9])[N:7]([CH2:10][CH2:11][O:12][CH2:13][CH3:14])[C:6]2[CH:15]=[CH:16][CH:17]=[CH:18][C:5]=2[C:4]2[CH:19]=[CH:20][CH:21]=[CH:22][C:3]1=2.[CH3:23][C:24]([CH3:39])([C:28]([NH:30][CH2:31][C:32]([F:38])([F:37])[C:33]([F:36])([F:35])[F:34])=[O:29])[C:25](O)=[O:26]>>[CH2:13]([O:12][CH2:11][CH2:10][N:7]1[C:8](=[O:9])[C@@H:2]([NH:1][C:25](=[O:26])[C:24]([CH3:23])([CH3:39])[C:28]([NH:30][CH2:31][C:32]([F:37])([F:38])[C:33]([F:34])([F:35])[F:36])=[O:29])[C:3]2[CH:22]=[CH:21][CH:20]=[CH:19][C:4]=2[C:5]2[CH:18]=[CH:17][CH:16]=[CH:15][C:6]1=2)[CH3:14]

Participants

3

Reactant 2

HCID 21072482HCID 21072482, compoundHCID 58972485(S)-7-amino-5-(2-ethoxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-one

Product 1

HCID 58972522HCID 58972522, compound

Procedure

Using (S)-7-amino-5-(2-ethoxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-one and 2,2-dimethyl-N-(2,2,3,3,3-pentafluoro-propyl)-malonamic acid, the title compound was prepared in the same manner as example 1c (80%). White solid. MS: m/e=542(M+H+).

Sources & evidence

ORD record
ord-d6a4f4c6c488464695ebd5dee03fb337
Source dataset
uspto-grants-2008_09
Patent number
US07425551B2

Reaction notes

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