Dimethyl Sulfoxide → 1-(3,5-difluorophenyl)cyclopentane-1-carboxylic acid
Reaction equation
[CH3:36][S:37]([CH3:38])=[O:39].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][CH:7]([c:8]2[cH:9][cH:10][cH:11][cH:12][cH:28]2)[CH:29]([NH:30][C:13](=[O:14])[C:15]2([c:20]3[cH:21][c:22]([F:27])[cH:23][c:24]([F:26])[cH:25]3)[CH2:16][CH2:17][CH2:18][CH2:19]2)[CH3:31])[cH:32][cH:33]1.[K+:35].[OH-:34].[OH2:40]>>[C:13]([OH:14])([C:15]1([c:20]2[cH:21][c:22]([F:27])[cH:23][c:24]([F:26])[cH:25]2)[CH2:16][CH2:17][CH2:18][CH2:19]1)=[O:34]Participants
6
Sources & evidence
- ORD record
- ord-472080711a3542b39600c7e1a9d7d45e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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