Methanol → 5-Bromo-1-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline
Reaction equation
[BH4-:24].[Br:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[C:7]([c:12]1[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)=[N:6][CH2:5][CH2:4]2.[CH3:22][OH:23].[Na+:25].[OH2:26]>>[Br:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[CH:7]([c:12]1[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)[NH:6][CH2:5][CH2:4]2Participants
6
Sources & evidence
- ORD record
- ord-2ca3d6d8733e4d7a95fde83fc6bb55a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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