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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 310653Generated: October 29, 2026

Diethyl Ether → 3-{[5-(trifluoromethyl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-1,3-benzodiazol-2-yl]methyl}cyclobutane-1-carbaldehyde

https://huagongshe.com/reaction/310653

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantTetrahydrofuranHCID 8028—
ReactantDiisobutylaluminum hydrideHCID 14487—
ReactantN-methoxy-N-methyl-3-{[5-(trifluoromethyl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-1,3-benzodiazol-2-yl]methyl}cyclobutane-1-carboxamideHCID 86666119—
Product3-{[5-(trifluoromethyl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-1,3-benzodiazol-2-yl]methyl}cyclobutane-1-carbaldehydeHCID 86666116—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-891efd4b757546c384ad8b060b1dc25b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)