Acetonitrile → 1-Cyclohexyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

HRID 311228Notes

Reaction equation

HRID 311228 reaction equation
[CH2:24]([CH3:25])[NH:26][CH2:27][CH:28]1[CH2:29][NH:30][CH2:31][CH2:32]1.[CH3:33][C:34]#[N:35].[CH:1]1([n:7]2[cH:8][c:9]([C:21](=[O:22])[OH:23])[c:10](=[O:20])[c:11]3[cH:12][c:13]([F:19])[c:14]([F:18])[c:15]([F:17])[c:16]23)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[CH:1]1([n:7]2[cH:8][c:9]([C:21](=[O:22])[OH:23])[c:10](=[O:20])[c:11]3[cH:12][c:13]([F:19])[c:14]([N:30]4[CH2:29][CH:28]([CH2:27][NH:26][CH2:24][CH3:25])[CH2:32][CH2:31]4)[c:15]([F:17])[c:16]23)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 13491786Ethyl-pyrrolidin-3-ylmethyl-amineHCID 137728341-Cyclohexyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Product 1

HCID 137728131-Cyclohexyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Sources & evidence

ORD record
ord-d257d7de0aac49c3b2a1410444e7769f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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