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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 311235Generated: October 30, 2026

Diethyl Ether → tert-Butyl 4-(5-(hydroxy(thiophen-2-yl)methyl)-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperazine-1-carboxylate

https://huagongshe.com/reaction/311235

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantDichloromethaneHCID 6344—
ReactantThiopheneHCID 8030—
ReactantTert-butyl 4-(5-formyl-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperazine-1-carboxylateHCID 58447024—
ReactantButyllithiumHCID 178418339—
Producttert-Butyl 4-(5-(hydroxy(thiophen-2-yl)methyl)-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperazine-1-carboxylateHCID 58446989—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-1cbfcabf0e0346a6a2d13b8d2231f095
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)