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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31124Generated: October 29, 2026

(R)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril → (S)-1-carboxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril

https://huagongshe.com/reaction/31124

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 69194658—
Reactant(S)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 69196603—
Reactant(R)-1-carboxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 69198269—
Product(S)-1-carboxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyrilHCID 69195122—

Reaction Steps

The title compound was prepared from (S)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril (Example 8) by the procedures described for the preparation of (R)-1-carboxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril (Example 9) from (R)-1-carbomethoxymethyl-3-(5-chloroindole-2-carbonylamino)-3,4-dihydrocarbostyril. HPLC/MS [M+H]+, 398.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425550B2
Source datasetuspto-grants-2008_09
ORD IDord-449490e87260440da46708e9912ea938
Source noteuspto-grants-2008_09