Toluene → tert-Butyl 4-(6-(6-bromo-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydro-pyrido(2,3-d)pyrimidin-2-ylamino)-pyridin-3-yl)-piperazine-1-carboxylate
Reaction equation
[Br:1][c:2]1[c:3]([CH3:21])[c:4]2[c:5]([n:6][c:7]([S:10]([CH3:11])=[O:12])[n:8][cH:9]2)[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15].[C:22]([CH3:23])([CH3:24])([CH3:25])[O:26][C:27](=[O:28])[N:29]1[CH2:30][CH2:31][N:32]([c:35]2[cH:36][n:37][c:38]([NH2:41])[cH:39][cH:40]2)[CH2:33][CH2:34]1.[CH3:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[Cl:49][CH2:50][Cl:51]>>[Br:1][c:2]1[c:3]([CH3:21])[c:4]2[c:5]([n:6][c:7]([NH:41][c:38]3[n:37][cH:36][c:35]([N:32]4[CH2:31][CH2:30][N:29]([C:27]([O:26][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:28])[CH2:34][CH2:33]4)[cH:40][cH:39]3)[n:8][cH:9]2)[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-346529c3f0f34090ab59b57742f837f2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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