2-[4-(1,1-Difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine → 5-(3,5-Difluoro-phenyl)-2-methyl-oxazole-4-carboxylic Acid {2-[4-(1,1-difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-yl}-amide

HRID 311366Notes

Reaction equation

HRID 311366 reaction equation
[F:17][c:18]1[cH:19][c:20](-[c:25]2[c:26]([C:31](=[O:32])[OH:33])[n:27][c:28]([CH3:30])[o:29]2)[cH:21][c:22]([F:24])[cH:23]1.[F:1][C:2]([CH3:3])([F:4])[c:5]1[n:6][c:7]([CH2:10][n:11]2[n:12][cH:13][c:14]([NH2:16])[n:15]2)[s:8][cH:9]1>>[F:1][C:2]([CH3:3])([F:4])[c:5]1[n:6][c:7]([CH2:10][n:11]2[n:12][cH:13][c:14]([NH:16][C:31]([c:26]3[c:25](-[c:20]4[cH:19][c:18]([F:17])[cH:23][c:22]([F:24])[cH:21]4)[o:29][c:28]([CH3:30])[n:27]3)=[O:32])[n:15]2)[s:8][cH:9]1

Participants

3

Reactant 2

HCID 671276722-[4-(1,1-Difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamineHCID 67127910HCID 67127910, compound

Product 1

HCID 498344225-(3,5-Difluoro-phenyl)-2-methyl-oxazole-4-carboxylic Acid {2-[4-(1,1-difluoro-ethyl)-thiazol-2-ylmethyl]-2H-[1,2,3]triazol-4-yl}-amide

Sources & evidence

ORD record
ord-b5dbb7d0126e40268a03e85b8a2f6926
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…