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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 311391Generated: October 31, 2026

Acetic Acid → 4-(3-Chlorophenyl)-2-{5-[2-(4-methyl-piperazin-1-yl)-ethyl]-2-nitro-phenylamino}-thiazole-5-carboxylic acid amide

https://huagongshe.com/reaction/311391

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantDiethyl EtherHCID 3283—
ReactantDichloromethaneHCID 6344—
Reactant1-MethylpiperazineHCID 53167—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant4-(3-Chloro-phenyl)-2-[2-nitro-5-(2-oxo-ethyl)-phenylamino]-thiazole-5-carboxylic acid amideHCID 86642812—
Product4-(3-Chlorophenyl)-2-{5-[2-(4-methyl-piperazin-1-yl)-ethyl]-2-nitro-phenylamino}-thiazole-5-carboxylic acid amideHCID 86642813—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-b032d487acc84b5d9318e73d74abeb7d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)