1-(Bromomethyl)-4-(trifluoromethyl)benzene → Ethyl 2-(3-(benzo[c][1,2,5]oxadiazol-5-ylmethyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate

HRID 311534Notes

Reaction equation

HRID 311534 reaction equation
[Br:13][CH2:14][c:15]1[cH:16][c:17]2[c:18]([n:19][o:20][n:21]2)[cH:22][cH:23]1.[CH3:24][c:25]1[n:26][c:27]([N:35]2[C:36](=[O:40])[NH:37][CH2:38][CH2:39]2)[s:28][c:29]1[C:30](=[O:31])[O:32][CH2:33][CH3:34].[F:1][C:2]([F:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:9][Br:10])[cH:11][cH:12]1>>[CH2:14]([c:15]1[cH:16][c:17]2[c:18]([n:19][o:20][n:21]2)[cH:22][cH:23]1)[N:37]1[C:36](=[O:40])[N:35]([c:27]2[n:26][c:25]([CH3:24])[c:29]([C:30](=[O:31])[O:32][CH2:33][CH3:34])[s:28]2)[CH2:39][CH2:38]1

Participants

4

Reactant 3

HCID 1230621-(Bromomethyl)-4-(trifluoromethyl)benzeneHCID 27355875-(Bromomethyl)-2,1,3-benzoxadiazoleHCID 57919776Ethyl 4-methyl-2-(2-oxoimidazolidin-1-yl)thiazole-5-carboxylate

Product 1

HCID 58031450Ethyl 2-(3-(benzo[c][1,2,5]oxadiazol-5-ylmethyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate

Sources & evidence

ORD record
ord-d6c0bbf290a74604a661b2cefe8b96bd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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