Methanol → 4-Benzyloxy-1-{2-hydroxy-2-[3-(2,2,2-trifluoro-acetyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl]-ethyl}-1H-pyridin-2-one
Reaction equation
[BH4-:36].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:35])[n:12]([CH2:15][C:16]([c:17]2[cH:18][c:19]3[c:20]([cH:32][cH:33]2)[CH2:21][CH2:22][N:23]([C:26]([C:27]([F:28])([F:29])[F:30])=[O:31])[CH2:24][CH2:25]3)=[O:34])[cH:13][cH:14]1.[CH3:38][OH:39].[Na+:37]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:35])[n:12]([CH2:15][CH:16]([c:17]2[cH:18][c:19]3[c:20]([cH:32][cH:33]2)[CH2:21][CH2:22][N:23]([C:26]([C:27]([F:28])([F:29])[F:30])=[O:31])[CH2:24][CH2:25]3)[OH:34])[cH:13][cH:14]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-1f6d940d1ffb491c8db49fe152d2b6b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…