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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 311604Generated: October 26, 2026

Hydrochloric Acid → 4-[(7R,7aS)-7-hydroxy-1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrile

https://huagongshe.com/reaction/311604

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-Chloro-4-isocyanato-3-methylbenzonitrileHCID 16731849—
ReactantMethyl 3-hydroxypyrrolidine-2-carboxylateHCID 22669281—
Product4-[(7R,7aS)-7-hydroxy-1,3-dioxo-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazol-2-yl]-2-chloro-3-methylbenzonitrileHCID 49823417—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-56fe527567794b6a909843debcbe0e57
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)