HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Fluorophenyl)chroman-6-ol → 2-(2,4-Dichlorophenyl)chroman-6-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Fluorophenyl)chroman-6-ol | HCID 17978471 | — |
| Reactant | 2-(2,4-Dichlorophenyl)chroman-4,6-diol | HCID 17978588 | — |
| Product | 2-(2,4-Dichlorophenyl)chroman-6-ol | HCID 17978555 | — |
Reaction Steps
2-(2,4-Dichlorophenyl)chroman-6-ol was prepared as described for 2-(3-fluorophenyl)chroman-6-ol in Example 9(c) starting from 625 mg of 2-(2,4-dichlorophenyl)chroman-4,6-diol. 1H NMR (400 MHz, d6-DMSO) δ: 8.85 (s, 1H), 7.65 (d, 1H, J 2.2 Hz), 7.57 (d, 1H, J 8.4 Hz), 7.49 (dd, 1H, J 8.4, 2.2 Hz), 6.67-6.51 (m, 3H), 5.21 (dd, 1H, J 10.3, 2.1 Hz), 2.91 (m, 1H), 2.69 (m, 1H), 2.16 (m, 1H), 1.85 (m, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425568B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-82ce174ba70e4be98d1c09ca94c8842b |
| Source note | uspto-grants-2008_09 |