HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Fluorophenyl)chroman-6-ol → 2-(2,5-Difluorophenyl)chroman-6-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Fluorophenyl)chroman-6-ol | HCID 17978471 | — |
| Reactant | 2-(2,5-Difluorophenyl)chroman-4,6-diol | HCID 17978594 | — |
| Product | 2-(2,5-Difluorophenyl)chroman-6-ol | HCID 17978526 | — |
Reaction Steps
2-(2,5-Difluorophenyl)chroman-6-ol was prepared as described for 2-(3-fluorophenyl)chroman-6-ol in Example 9(c) starting from 420 mg of 2-(2,5-difluorophenyl)chroman-4,6-diol. 1H NMR (300 MHz, d6-DMSO) δ: 8.82 (s, 1H), 7.34-7.22 (m, 3H), 6.71-6.51 (m, 3H), 5.20 (m, 1H), 2.93 (m, 1H), 2.68 (m, 1H), 2.11 (m, 1H), 1.98 (m, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425568B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-1ee2239100544a389f4848c80798ef13 |
| Source note | uspto-grants-2008_09 |