Acetate → tert-butyl N-[1-[3-[[2-(2-fluorophenyl)-1,3-thiazole-4-carbonyl]amino]-4-pyridinyl]piperidin-3-yl]carbamate
Reaction equation
[Br:1][c:2]1[s:3][cH:4][c:5]([C:7](=[O:8])[NH:9][c:10]2[cH:11][n:12][cH:13][cH:14][c:15]2[N:16]2[CH2:17][CH:18]([NH:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:19][CH2:20][CH2:21]2)[n:6]1.[CH3:41][C:42](=[O:43])[O-:44].[CH3:52][C:53]#[N:54].[F:30][c:31]1[c:32]([B:37]([OH:38])[OH:39])[cH:33][cH:34][cH:35][cH:36]1.[K+:40].[Na+:46].[Na+:47].[O-:48][C:49](=[O:50])[O-:51].[OH2:45]>>[c:2]1(-[c:32]2[c:31]([F:30])[cH:36][cH:35][cH:34][cH:33]2)[s:3][cH:4][c:5]([C:7](=[O:8])[NH:9][c:10]2[cH:11][n:12][cH:13][cH:14][c:15]2[N:16]2[CH2:17][CH:18]([NH:22][C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:19][CH2:20][CH2:21]2)[n:6]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-2ff53877b7854ade946b531440a0a803
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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