Dichloromethane → {5-[7-(3-Methanesulfonyl-phenyl)-4-morpholin-4-yl-quinazolin-2-yl]-pyridine-2-yl}-carbamic acid 2,2,2-trichloroethyl ester
Reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7](-[c:11]2[cH:12][cH:13][c:14]3[c:15]([N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[n:16][c:17](-[c:21]4[cH:22][cH:23][c:24]([NH2:27])[n:25][cH:26]4)[n:18][c:19]3[cH:20]2)[cH:8][cH:9][cH:10]1.[Cl:34][C:35]([CH2:36][O:37][C:38](=[O:39])[Cl:40])([Cl:41])[Cl:42].[Cl:43][CH2:44][Cl:45]>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][c:7](-[c:11]2[cH:12][cH:13][c:14]3[c:15]([N:28]4[CH2:29][CH2:30][O:31][CH2:32][CH2:33]4)[n:16][c:17](-[c:21]4[cH:22][cH:23][c:24]([NH:27][C:38]([O:37][CH2:36][C:35]([Cl:34])([Cl:41])[Cl:42])=[O:39])[n:25][cH:26]4)[n:18][c:19]3[cH:20]2)[cH:8][cH:9][cH:10]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-819c581a762b4f458b89020a781de58e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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