HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Fluorophenyl)chroman-6-ol → 3-Methyl-2-phenylchroman-6-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Fluorophenyl)chroman-6-ol | HCID 17978471 | — |
| Reactant | 3-Methyl-2-phenylchroman-4,6-diol | HCID 17978630 | — |
| Product | 3-Methyl-2-phenylchroman-6-ol | HCID 20457866 | — |
Reaction Steps
3-Methyl-2-phenylchroman-6-ol was prepared as described for 2-(3-fluorophenyl)chroman-6-ol in Example 9(c) starting from 605 mg of 3-methyl-2-phenylchroman-4,6-diol. 1H NMR (400 MHz, CD3OD) δ: 8.77 (s, 1H), 7.41-7.33 (m, 5H), 6.59-6.48 (m, 3H), 4.56 (d, 1H, J 9.2 Hz), 2.73 (dd, 1H, J −16.5, 5.0 Hz), 2.54 (dd, 1H, J −116.5, 5.8 Hz), 2.11 (m, 1H), 0.72 (d, 3H, J 6.6 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425568B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-5c830334844446c5aae6885d08d8836d |
| Source note | uspto-grants-2008_09 |