3-Chloro-4-fluoro-1-benzothiophene-2-carbonyl chloride → tert-Butyl (4-{(3-chloro-4-fluoro-benzo[b]thiophene-2-carbonyl)-[4'-(formyl-methyl-amino)-4-methoxy-biphenyl-3-ylmethyl]-amino}-cyclohexyl)-methyl-carbamate
Reaction equation
[CH:1](=[O:2])[N:3]([c:4]1[cH:5][cH:6][c:7](-[c:10]2[cH:11][c:12]([CH2:18][NH:19][CH:20]3[CH2:21][CH2:22][CH:23]([N:26]([C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH3:34])[CH2:24][CH2:25]3)[c:13]([O:16][CH3:17])[cH:14][cH:15]2)[cH:8][cH:9]1)[CH3:35].[Cl:36][c:37]1[c:38]2[c:39]([s:40][c:41]1[C:42](=[O:43])[Cl:44])[cH:45][cH:46][cH:47][c:48]2[F:49]>>[CH:1](=[O:2])[N:3]([c:4]1[cH:5][cH:6][c:7](-[c:10]2[cH:11][c:12]([CH2:18][N:19]([CH:20]3[CH2:21][CH2:22][CH:23]([N:26]([C:27]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:33])[CH3:34])[CH2:24][CH2:25]3)[C:42]([c:41]3[c:37]([Cl:36])[c:38]4[c:39]([s:40]3)[cH:45][cH:46][cH:47][c:48]4[F:49])=[O:43])[c:13]([O:16][CH3:17])[cH:14][cH:15]2)[cH:8][cH:9]1)[CH3:35]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a20f857b85fc43a6b3517af553cce01d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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