HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 312288Generated: October 30, 2026
Hydrochloric Acid → 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-(4-chlorophenyl)-6-fluoro-3,4-dihydroisoquinoline-2(1H)-carboxamide
https://huagongshe.com/reaction/312288
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-(6-Fluoro-1,2,3,4-tetrahydroisoquinolin-7-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine | HCID 59496648 | — |
| Product | 7-[2-amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N-(4-chlorophenyl)-6-fluoro-3,4-dihydroisoquinoline-2(1H)-carboxamide | HCID 59496635 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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| ORD ID | ord-ae8d0a7db43740239d1e41e342d03ef8 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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