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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31244Generated: October 26, 2026

3-Fluorophenylacetic acid → 2-(3-Fluorophenyl)indan-5-ol

https://huagongshe.com/reaction/31244

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluorophenylacetic acidHCID 67617—
Reactant2-Phenylindan-5-olHCID 17978448—
Product2-(3-Fluorophenyl)indan-5-olHCID 17978508—

Reaction Steps

2-(3-Fluorophenyl)indan-5-ol was prepared as described for 2-phenylindan-5-ol in Example 25(a-e) using 5 g of 3-fluorophenylacetic acid. 1H-NMR (400 MHz, d6-DMSO): 9.09 (s, 1H), 7.37-7.29 (m, 1H), 7.14-7.7.09 (m, 2H), 7.02-6.98 (m, 2H), 6.64 (d, 1H, J 1.7 Hz), 6.55 (dd, 1H, J 2.3, 8.1 Hz), 3.63 (k, 1H, J 8.3 Hz), 3.24-3.12 (m, 2H), 2.94-2.79 (m, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425568B2
Source datasetuspto-grants-2008_09
ORD IDord-ad77a607e21b46009db757a8370ec371
Source noteuspto-grants-2008_09