Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31246Generated: October 28, 2026

5-(2-Nitrophenoxy)-2-phenylindane → 2-(2-Phenylindan-5-yloxy)phenylamine

https://huagongshe.com/reaction/31246

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(2-Nitrophenoxy)-2-phenylindaneHCID 17978534—
Reactant2-(2-Phenylchroman-6-yloxy)-anilineHCID 17978558—
Product2-(2-Phenylindan-5-yloxy)phenylamineHCID 17978652—

Reaction Steps

2-(2-Phenylindan-5-yloxy)phenylamine was prepared as described for 2-(2-phenylchroman-6yloxy)-phenylamine in Example 29(b) using 170 mg of 5-(2-nitrophenoxy)-2-phenylindane. 1H-N (400 MHz, d6-DMSO): 7.32-7.27 (m, 4H), 7.23-7.16 (m, 2H), 6.92-6.87 (m, 1H), 6.81-6.71 (m, 4H), 6.56-6.53 (m, 1H), 4.85 (bs, 2H), 3.65 (k, 1H, J 8.3 Hz), 3.23 (dd, 2H, J 8.3, 15.5 Hz), 2.97-2.88 (m, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425568B2
Source datasetuspto-grants-2008_09
ORD IDord-e33490f44b364434a807068d3670c16d
Source noteuspto-grants-2008_09