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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 312602Generated: November 2, 2026

Acetate → 1-(4-(Difluoromethoxy)-3-methylphenyl)-3,5-dimethylpiperazine

https://huagongshe.com/reaction/312602

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetateHCID 175—
ReactantPotassium CationHCID 813—
ReactantTolueneHCID 1140—
Reactant2,6-DimethylpiperazineHCID 66056—
ReactantAllyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 105144—
ReactantBinap, (A+-)-HCID 634876—
Reactant2-Methylpropan-2-olateHCID 4574913—
Reactant4-Bromo-1-(difluoromethoxy)-2-methylbenzeneHCID 45158710—
Product1-(4-(Difluoromethoxy)-3-methylphenyl)-3,5-dimethylpiperazineHCID 67045807—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-3610792d2a8b4de2b3bd76d8e2bd3784
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)