N-[2-(aminosulfonyl)-4-bromophenyl]-1-benzyl-4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide → 1-butyl-3-(1,1-dioxido-4H-pyrido[3,2-e][1,2,4]thiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinone
Reaction equation
[NH2:1][S:2](=[O:3])(=[O:4])[c:5]1[n:6][cH:7][cH:8][cH:9][c:10]1[NH:11][C:12](=[O:13])[c:14]1[c:15](=[O:29])[n:16]([CH2:25][CH2:26][CH2:27][CH3:28])[c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]2[c:23]1[OH:24].[NH2:30][S:31]([c:32]1[cH:33][c:34]([Br:35])[cH:36][cH:37][c:38]1[NH:39][C:40]([c:41]1[c:42](=[O:43])[n:44]([CH2:45][c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[c:52]2[c:53]([c:54]1[OH:55])[cH:56][cH:57][cH:58][n:59]2)=[O:60])(=[O:61])=[O:62]>>[N:1]1=[C:12]([c:14]2[c:15](=[O:29])[n:16]([CH2:25][CH2:26][CH2:27][CH3:28])[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]3[c:23]2[OH:24])[NH:11][c:10]2[c:5]([n:6][cH:7][cH:8][cH:9]2)[S:2]1(=[O:3])=[O:4]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d7d41ccaec924c66a67a3d312fd9c335
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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