tert-Butyl piperazine-1-carboxylate → 4-[5-(3-Tert-butyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH:11][C:12]([c:13]2[cH:14][n:15][c:16]([Cl:19])[cH:17][cH:18]2)=[O:20])[cH:8][cH:9][cH:10]1.[C:21](=[O:22])([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[N:28]1[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]1.[C:34]([O:35][C:36]([N:37]1[CH2:38][CH2:39][N:40]([c:41]2[cH:42][cH:43][c:44]([C:45](=[O:46])[NH:47][c:48]3[cH:49][cH:50][c:51]([CH3:52])[c:53]([I:54])[cH:55]3)[cH:56][n:57]2)[CH2:58][CH2:59]1)=[O:60])([CH3:61])([CH3:62])[CH3:63]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][c:7]([NH:11][C:12]([c:13]2[cH:14][n:15][c:16]([N:31]3[CH2:30][CH2:29][N:28]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:33][CH2:32]3)[cH:17][cH:18]2)=[O:20])[cH:8][cH:9][cH:10]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-6c95d34dc07b4f21b523c9eb09abb335
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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