HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Fluorophenyl)chroman-6-ol → 2-(4-Fluorophenyl)chroman-6-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Fluorophenyl)chroman-6-ol | HCID 17978471 | — |
| Reactant | 2-(4-Fluorophenyl)chroman-4,6-diol | HCID 17978560 | — |
| Product | 2-(4-Fluorophenyl)chroman-6-ol | HCID 17978481 | — |
Reaction Steps
2-(4-Fluorophenyl)chroman-6-ol was prepared as described for 2-(3-fluorophenyl)chroman-6-ol in Example 9(c) starting from 480 mg of 2-(4-fluorophenyl)-chroman-4,6-diol. 1H NMR (400 MHz, CDCl3) δ: 7.38 (m, 2H), 7.06 (m, 2H), 6.77 (d, 1H, J 8.6 Hz), 6.61 (dd, 1H, J 8.6, 2.9 Hz), 6.57 (d, 1H, 8.6 Hz), 4.97 (dd, 1H, J 10.2, 2.4 Hz), 2.95 (ddd, 1H, J −16.8, 11.4, 6.2 Hz), 2.74 (ddd, 1H, J −16.8, 5.3, 3.1 Hz), 2.15 (m, 1H), 2.05 (m, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425568B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-59c26eb6547e4d4cbeb33cf3e7cf01f8 |
| Source note | uspto-grants-2008_09 |