2-Aminopyrimidine-5-boronic acid, pinacol ester → 5-{3-[4-(4-Chloro-phenyl)-6-methyl-pyridin-2-yl]-phenyl}-pyrimidin-2-ylamine

HRID 313303Notes

Reaction equation

HRID 313303 reaction equation
[Br:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]([CH3:21])[cH:11][c:12](-[c:14]3[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[cH:13]2)[cH:5][cH:6][cH:7]1.[NH2:22][c:23]1[n:24][cH:25][c:26]([B:29]2[O:30][C:31]([CH3:32])([CH3:33])[C:34]([CH3:35])([CH3:36])[O:37]2)[cH:27][n:28]1>>[c:2]1(-[c:26]2[cH:25][n:24][c:23]([NH2:22])[n:28][cH:27]2)[cH:3][c:4](-[c:8]2[n:9][c:10]([CH3:21])[cH:11][c:12](-[c:14]3[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]3)[cH:13]2)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 177502122-Aminopyrimidine-5-boronic acid, pinacol esterHCID 574687502-(3-Bromo-phenyl)-4-(4-chloro-phenyl)-6-methylpyridine

Product 1

HCID 602093795-{3-[4-(4-Chloro-phenyl)-6-methyl-pyridin-2-yl]-phenyl}-pyrimidin-2-ylamine

Sources & evidence

ORD record
ord-1d461683d68941648d18e1b5eca87467
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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