Dichloromethane → Tert-butyl 2-{[(4,4-dimethyl-2-oxohexyl)amino]carbonyl}-4,4-difluoro-2-[4-(5-fluoropyridin-2-yl)benzyl]pyrrolidine-1-carboxylate
Reaction equation
[Cl:41][CH2:42][Cl:43].[F:1][C:2]1([F:40])[CH2:3][C:4]([C:14](=[O:15])[NH:16][CH2:17][CH:18]([CH2:19][C:20]([CH2:21][CH3:22])([CH3:23])[CH3:24])[OH:25])([CH2:26][c:27]2[cH:28][cH:29][c:30](-[c:33]3[n:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[cH:31][cH:32]2)[N:5]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:6]1>>[F:1][C:2]1([F:40])[CH2:3][C:4]([C:14](=[O:15])[NH:16][CH2:17][C:18]([CH2:19][C:20]([CH2:21][CH3:22])([CH3:23])[CH3:24])=[O:25])([CH2:26][c:27]2[cH:28][cH:29][c:30](-[c:33]3[n:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[cH:31][cH:32]2)[N:5]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:6]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f068ac6700eb4417a8cd6ed14f31ade1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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